5'-fluoro-3,4-dihydro-5H-spiro[furan-2,3'-indoline]-2',5-dione
Reagent
Code: #193173
CAS Number
1983145-88-5
science Other reagents with same CAS 1983145-88-5
blur_circular Chemical Specifications
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Molecular Information
Weight
221.188 g/mol
Formula
C₁₁H₈FNO₃
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of kinase inhibitors for cancer therapy. Its spirocyclic structure with a fluorine substituent enhances binding selectivity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its rigid framework and ability to mimic peptide motifs. Also utilized in the preparation of bioactive molecules targeting neurological disorders and inflammatory diseases.
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