tert-Butyl 6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-bromopicolinate
97%
Reagent
Code: #193160
CAS Number
1235036-16-4
blur_circular Chemical Specifications
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Molecular Information
Weight
565.48 g/mol
Formula
C₂₇H₂₅BrN₄O₃S
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Storage & Handling
Storage
-20°C, away from light, dry
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of potent kinase inhibitors, particularly targeting tyrosine kinases involved in cancer cell proliferation. Its structure enables strong binding to enzyme active sites, enhancing inhibitory activity. The benzo[d]thiazole and dihydroisoquinoline moieties contribute to improved metabolic stability and selectivity. Commonly employed in the development of targeted therapies for solid tumors and hematological malignancies. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug candidates for better potency and pharmacokinetic profiles.
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