5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

95%

Reagent Code: #192702
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CAS Number 452105-33-8

science Other reagents with same CAS 452105-33-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 300.28 g/mol
Formula C₁₆H₁₃FN₂O₃
badge Registry Numbers
MDL Number MFCD09835575
thermostat Physical Properties
Melting Point >295 °C(dec.)
Boiling Point 588.4±50.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.454±0.06 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in the development of pharmaceuticals that inhibit abnormal cell signaling pathways in tumors. Its structure supports binding to specific kinase enzymes, making it valuable in oncology drug research. Also utilized in the preparation of small-molecule inhibitors for use in chronic myeloid leukemia and other solid tumor treatments. Commonly involved in the production of sunitinib analogs due to its ability to enhance selectivity and potency in kinase inhibition.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,530.00
inventory 250mg
10-20 days ฿5,910.00
inventory 1g
10-20 days ฿15,620.00
inventory 5g
10-20 days ฿51,810.00

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5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
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Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in the development of pharmaceuticals that inhibit abnormal cell signaling pathways in tumors. Its structure supports binding to specific kinase enzymes, making it valuable in oncology drug research. Also utilized in the preparation of small-molecule inhibitors for use in chronic myeloid leukemia and other solid tumor treatments. Commonly involved in the production of sunitinib analogs due to its ability to enhance selectivity and potency in kinase inhibition.
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