5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
95%
Reagent
Code: #192702
CAS Number
452105-33-8
science Other reagents with same CAS 452105-33-8
blur_circular Chemical Specifications
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Molecular Information
Weight
300.28 g/mol
Formula
C₁₆H₁₃FN₂O₃
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Registry Numbers
MDL Number
MFCD09835575
thermostat
Physical Properties
Melting Point
>295 °C(dec.)
Boiling Point
588.4±50.0 °C(Predicted)
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Storage & Handling
Density
1.454±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in the development of pharmaceuticals that inhibit abnormal cell signaling pathways in tumors. Its structure supports binding to specific kinase enzymes, making it valuable in oncology drug research. Also utilized in the preparation of small-molecule inhibitors for use in chronic myeloid leukemia and other solid tumor treatments. Commonly involved in the production of sunitinib analogs due to its ability to enhance selectivity and potency in kinase inhibition.
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