5-Benzyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
98%
Reagent
Code: #192457
CAS Number
419547-73-2
science Other reagents with same CAS 419547-73-2
blur_circular Chemical Specifications
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Molecular Information
Weight
335.79 g/mol
Formula
C₁₉H₁₄ClN₃O
thermostat
Physical Properties
Boiling Point
538.2±60.0 °C(Predicted)
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Storage & Handling
Density
1.33±0.1 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK2 and CDK9, which play key roles in cell cycle regulation and transcription. This compound shows promise in oncology for disrupting cancer cell proliferation and inducing apoptosis in tumor cells. It serves as a lead structure in the development of anticancer agents, especially in studies targeting leukemia and solid tumors. Its scaffold is also explored for optimizing pharmacokinetic properties in kinase inhibitor drug design.
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