GNF-2
10mM in DMSO
Reagent
Code: #190174
CAS Number
778270-11-4
science Other reagents with same CAS 778270-11-4
blur_circular Chemical Specifications
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Molecular Information
Weight
374.32 g/mol
Formula
C₁₈H₁₃F₃N₄O₂
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Registry Numbers
MDL Number
MFCD09265253
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Storage & Handling
Storage
-20°C
description Product Description
Used in research to inhibit Bcr-Abl tyrosine kinase, particularly in chronic myeloid leukemia (CML) studies. It targets the myristoyl pocket of the Abl kinase domain and is often explored in combination therapies to overcome drug resistance. Primarily serves as a tool compound in biochemical assays and cellular models to understand kinase regulation and support development of targeted cancer treatments.
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