Used in research to study TrkA kinase inhibition, particularly in models of cancer and neurodegenerative diseases. Shows potent activity against tumor cell proliferation in vitro, especially in neuroblastoma and certain carcinoma lines. Investigated for its ability to cross the blood-brain barrier, making it relevant for central nervous system disease models. Also employed as a selective tool compound to dissect signaling pathways involving NGF/TrkA in neuronal survival and differentiation. Not used clinically; strictly for preclinical research.