Used in research to modulate cellular signaling pathways, particularly in studies related to neurodegenerative diseases such as Alzheimer's, where GSK3β overactivity is implicated. Helps in investigating the role of glycogen synthase kinase-3 beta in insulin signaling, making it relevant to diabetes research. Also applied in cancer studies, as inhibition of GSK3β can influence cell proliferation and apoptosis. Commonly used in in vitro assays to assess pathway-specific effects and screen potential therapeutic targets.