[4-fluoro-3-(piperidine-1-carbonyl)phenyl]boronic acid
98%
Reagent
Code: #189531
CAS Number
874219-30-4
blur_circular Chemical Specifications
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Molecular Information
Weight
251.06 g/mol
Formula
C₁₂H₁₅BFNO₃
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Registry Numbers
MDL Number
MFCD08235049
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic acid functional group enables participation in Suzuki-Miyaura cross-coupling reactions, facilitating the construction of complex biaryl structures found in bioactive molecules. Commonly employed in medicinal chemistry for lead optimization due to its ability to enhance binding affinity and metabolic stability. Also utilized in the preparation of protease inhibitors, including those targeting serine proteases involved in disease pathways.
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