(2-Fluoro-5-(piperidine-1-carbonyl)phenyl)boronic acid
98%
Reagent
Code: #189234
CAS Number
874289-43-7
science Other reagents with same CAS 874289-43-7
blur_circular Chemical Specifications
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Molecular Information
Weight
251.06 g/mol
Formula
C₁₂H₁₅BFNO₃
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Registry Numbers
MDL Number
MFCD08436068
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic acid group enables Suzuki-Miyaura cross-coupling reactions, allowing efficient construction of biaryl structures in drug molecules. The presence of fluorine enhances binding affinity and metabolic stability in final active pharmaceutical ingredients. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate electronic and steric properties. Also utilized in the preparation of proteolysis targeting chimeras (PROTACs) and other targeted therapies.
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