(2-Fluoro-5-(piperidine-1-carbonyl)phenyl)boronic acid

98%

Reagent Code: #189234
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CAS Number 874289-43-7

science Other reagents with same CAS 874289-43-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 251.06 g/mol
Formula C₁₂H₁₅BFNO₃
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MDL Number MFCD08436068
inventory_2 Storage & Handling
Storage 2-8°C, Inert Gas

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic acid group enables Suzuki-Miyaura cross-coupling reactions, allowing efficient construction of biaryl structures in drug molecules. The presence of fluorine enhances binding affinity and metabolic stability in final active pharmaceutical ingredients. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate electronic and steric properties. Also utilized in the preparation of proteolysis targeting chimeras (PROTACs) and other targeted therapies.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,670.00
inventory 250mg
10-20 days ฿4,500.00
inventory 1g
10-20 days ฿12,100.00

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(2-Fluoro-5-(piperidine-1-carbonyl)phenyl)boronic acid
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Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic acid group enables Suzuki-Miyaura cross-coupling reactions, allowing efficient construction of biaryl structures in drug molecules. The presence of fluorine enhances binding affinity and metabolic stability in final active pharmaceutical ingredients. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate electronic and steric properties. Also utilized in the preparation of proteolysis targeting chimeras (PROTACs) and other targeted therapies.
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