4-(6-Fluoro-7-(4-methyl-1-piperazinyl)-2-[2-(5-nitro-2-furyl)vinyl]-4-quinazolinylamino)phenol
95%
Reagent
Code: #188398
CAS Number
844692-04-2
science Other reagents with same CAS 844692-04-2
blur_circular Chemical Specifications
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Molecular Information
Weight
490.49 g/mol
Formula
C₂₅H₂₃FN₆O₄
thermostat
Physical Properties
Boiling Point
585.4±50.0 °C
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Storage & Handling
Density
1.443±0.06 g/cm3
Storage
2-8°C
description Product Description
Used in research as a potent inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Shows potential in studies targeting cancer cell proliferation, particularly in non-small cell lung cancer and other solid tumors. Its structure allows selective binding to mutant forms of EGFR, making it valuable in developing targeted therapies. Also employed in biochemical assays to study signal transduction pathways involved in tumor growth and resistance mechanisms. Not used clinically but serves as a key compound in structure-activity relationship studies for next-generation kinase inhibitors.
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