(4'-Fluoro-[1,1'-biphenyl]-2-yl)methanamine
97%
Reagent
Code: #188374
CAS Number
884504-18-1
blur_circular Chemical Specifications
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Molecular Information
Weight
201.24 g/mol
Formula
C₁₃H₁₂FN
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Registry Numbers
MDL Number
MFCD05864430
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Physical Properties
Boiling Point
334.6°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure allows for effective binding in receptor sites, making it valuable in drug discovery for oncology and inflammatory diseases. The fluorinated biphenyl group enhances metabolic stability and membrane permeability, improving the pharmacokinetic profile of drug candidates. Also employed in the preparation of chiral ligands and catalysts for asymmetric synthesis.
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