Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in the preparation of active pharmaceutical ingredients (APIs) targeting epidermal growth factor receptor (EGFR) and other tyrosine kinases. Its fluorinated quinazoline core enhances binding affinity and metabolic stability in drug candidates. Commonly employed in research and development of targeted therapies for non-small cell lung cancer and other solid tumors. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.