4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-ol

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Reagent Code: #184961
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CAS Number 905306-05-0

science Other reagents with same CAS 905306-05-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 291.30 g/mol
Formula C₁₇H₁₃N₃O₂
badge Registry Numbers
MDL Number MFCD28965345
thermostat Physical Properties
Melting Point 252-254 °C
Boiling Point 491.9±45.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.36±0.1 g/cm3(Predicted)
Storage Room temperature, seal, dry

description Product Description

Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors for targeted cancer therapies, such as those for non-small cell lung cancer (NSCLC). This quinazoline derivative serves as a building block in medicinal chemistry to develop selective kinase inhibitors that target mutant forms of EGFR. It supports research into optimizing drug potency, selectivity, and pharmacokinetic properties, including potential blood-brain barrier penetration in final drug candidates.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿5,810.00

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4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-ol
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Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors for targeted cancer therapies, such as those for non-small cell lung cancer (NSCLC). This quinazoline derivative serves as a building block in medicinal chemistry to develop selective kinase inhibitors that target mutant forms of EGFR. It supports research into optimizing drug potency, selectivity, and pharmacokinetic properties, including potential blood-brain barrier penetration in final drug candidates.

Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors for targeted cancer therapies, such as those for non-small cell lung cancer (NSCLC). This quinazoline derivative serves as a building block in medicinal chemistry to develop selective kinase inhibitors that target mutant forms of EGFR. It supports research into optimizing drug potency, selectivity, and pharmacokinetic properties, including potential blood-brain barrier penetration in final drug candidates.

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