Erlotinib
10mM in DMSO
Reagent
Code: #181377
CAS Number
183321-74-6
blur_circular Chemical Specifications
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Molecular Information
Weight
393.44 g/mol
Formula
C₂₂H₂₃N₃O₄
thermostat
Physical Properties
Melting Point
223-228 °C
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of non-small cell lung cancer (NSCLC), especially in patients with specific epidermal growth factor receptor (EGFR) mutations. It works by inhibiting the EGFR tyrosine kinase, which helps block tumor cell proliferation and angiogenesis. Also used in pancreatic cancer treatment, typically in combination with chemotherapy like gemcitabine, to improve survival rates. Its targeted action makes it effective in cancers driven by EGFR overexpression or mutations, offering a more tailored approach compared to conventional chemotherapy.
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