E7080 (Lenvatinib)
10mM in DMSO
Reagent
Code: #181346
CAS Number
417716-92-8
science Other reagents with same CAS 417716-92-8
blur_circular Chemical Specifications
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Molecular Information
Weight
426.85 g/mol
Formula
C₂₁H₁₉ClN₄O₄
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Registry Numbers
MDL Number
MFCD16038644
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in oncology, this compound is effective in the treatment of differentiated thyroid cancer, particularly when the disease is progressive and radioactive iodine therapy is not suitable. It also plays a key role in managing advanced renal cell carcinoma, often in combination with immunotherapeutic agents. Additionally, it is approved for use in certain cases of hepatocellular carcinoma, offering an option for patients who cannot undergo surgical resection. Its mechanism involves inhibiting multiple receptor tyrosine kinases involved in tumor angiogenesis, progression, and metastasis, thereby helping to slow or halt cancer growth.
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