4-[[4-[[4-[(E)-2-cyanoethenyl]-2, 6-dimethyl-phenyl]amino]pyrimidin-2-yl]amino]benzonitrile

10mM in DMSO

Reagent Code: #181306
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CAS Number 500287-72-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 366.42 g/mol
Formula C₂₂H₁₈N₆
thermostat Physical Properties
Melting Point 245 °C
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in the development of pharmaceuticals that inhibit abnormal protein signaling in tumor cells, especially in treatments for chronic myeloid leukemia (CML) and non-small cell lung cancer (NSCLC). Its structure enables strong binding to specific kinase domains, enhancing the selectivity and efficacy of the drug while minimizing off-target effects. Also investigated for use in next-generation anticancer agents due to its stability and ability to cross cell membranes effectively.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿1,850.00

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