2-(2, 3-Dioxoindolin-1-yl)acetic acid
95%
Reagent
Code: #177927
CAS Number
60705-96-6
blur_circular Chemical Specifications
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Molecular Information
Weight
205.17 g/mol
Formula
C₁₀H₇NO₄
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Registry Numbers
MDL Number
MFCD00022920
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Physical Properties
Boiling Point
445.4 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. It serves as a building block for indolinone-based compounds that exhibit biological activity against various tumor cell lines. Also employed in the preparation of tyrosine kinase and cyclin-dependent kinase inhibitors. Its structure allows for easy functionalization, making it valuable in medicinal chemistry for structure-activity relationship studies. Additionally, it is utilized in the design of small molecule therapeutics targeting signal transduction pathways involved in cell proliferation and apoptosis.
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