Used in pharmaceutical research as a deuterated analog for metabolic stability studies, particularly in oncology drug development. Its primary application lies in investigating tyrosine kinase inhibition with improved pharmacokinetic properties. Commonly employed in tracer studies to monitor drug distribution and clearance in preclinical models. Also utilized in mass spectrometry assays due to enhanced detection sensitivity from deuterium labeling. Shows potential in optimizing dosing regimens for anti-angiogenic therapies targeting solid tumors.