5-((5-(2,8-Dimethyl-5H-dibenzo[a,d][7]annulen-5-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)furan-2-carboxamide

98%

Reagent Code: #167258
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CAS Number 216657-60-2

science Other reagents with same CAS 216657-60-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 537.59 g/mol
Formula C₂₈H₂₃N₇O₃S
inventory_2 Storage & Handling
Density 1.51±0.1 g/cm3(Predicted)
Storage -20°C, Inert Gas

description Product Description

Used in pharmaceutical research as a potent inhibitor of specific kinase enzymes involved in inflammatory and oncogenic signaling pathways. Shows promise in preclinical studies for targeted cancer therapy, particularly in tumors driven by overexpression of receptor tyrosine kinases. Its structure, featuring a furan carboxamide linked to a tetrazole and a substituted dihydropyrimidinone-thione core with a dibenzoannulene moiety, enables high selectivity and binding affinity, improving efficacy while reducing off-target effects. Also investigated for anti-inflammatory applications due to modulation of immune cell activity. Currently under evaluation for optimization of bioavailability and metabolic stability in drug development pipelines.

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Size Availability Unit Price Quantity
inventory 1mg
10-20 days ฿13,900.00
inventory 10mg
10-20 days ฿62,450.00
inventory 25mg
10-20 days ฿106,140.00

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5-((5-(2,8-Dimethyl-5H-dibenzo[a,d][7]annulen-5-yl)-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-N-(1H-tetrazol-5-yl)furan-2-carboxamide
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Used in pharmaceutical research as a potent inhibitor of specific kinase enzymes involved in inflammatory and oncogenic signaling pathways. Shows promise in preclinical studies for targeted cancer therapy, particularly in tumors driven by overexpression of receptor tyrosine kinases. Its structure, featuring a furan carboxamide linked to a tetrazole and a substituted dihydropyrimidinone-thione core with a dibenzoannulene moiety, enables high selectivity and binding affinity, improving efficacy while reduc

Used in pharmaceutical research as a potent inhibitor of specific kinase enzymes involved in inflammatory and oncogenic signaling pathways. Shows promise in preclinical studies for targeted cancer therapy, particularly in tumors driven by overexpression of receptor tyrosine kinases. Its structure, featuring a furan carboxamide linked to a tetrazole and a substituted dihydropyrimidinone-thione core with a dibenzoannulene moiety, enables high selectivity and binding affinity, improving efficacy while reducing off-target effects. Also investigated for anti-inflammatory applications due to modulation of immune cell activity. Currently under evaluation for optimization of bioavailability and metabolic stability in drug development pipelines.

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