3-Cyano-N-(3-(1-Isobutyrylpiperidin-4-Yl)-1-Methyl-4-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridin-5-Yl)Benzamide
98%
Reagent
Code: #166877
CAS Number
1892576-58-7
blur_circular Chemical Specifications
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Molecular Information
Weight
497.51 g/mol
Formula
C₂₆H₂₆F₃N₅O₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 2 (JAK2), particularly in the development of treatments for autoimmune diseases and inflammatory conditions. It modulates cytokine signaling pathways involved in immune response, showing potential in models of rheumatoid arthritis, psoriasis, and other chronic inflammatory disorders. Due to its ability to cross the blood-brain barrier, it is also investigated for neuroinflammatory diseases. Its structure allows for high target specificity, reducing off-target effects in cellular assays. Currently utilized primarily as a preclinical tool compound for validating JAK2-dependent pathways in disease models.
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