3-Cyano-N-(3-(1-Isobutyrylpiperidin-4-Yl)-1-Methyl-4-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridin-5-Yl)Benzamide
98%
science Other reagents with same CAS 1892576-58-7
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description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 2 (JAK2), particularly in the development of treatments for autoimmune diseases and inflammatory conditions. It modulates cytokine signaling pathways involved in immune response, showing potential in models of rheumatoid arthritis, psoriasis, and other chronic inflammatory disorders. Due to its ability to cross the blood-brain barrier, it is also investigated for neuroinflammatory diseases. Its structure allows for high target specificity, reducing off-target effects in cellular assays. Currently utilized primarily as a preclinical tool compound for validating JAK2-dependent pathways in disease models.
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