Used as a potent and selective JAK1 (Janus kinase 1) inhibitor in pharmaceutical research, particularly in the development of kinase-targeted therapies for inflammatory and autoimmune diseases. It exhibits significant activity against JAK1, a tyrosine kinase involved in cytokine signaling pathways related to inflammation. Its structure provides high selectivity and binding affinity, making it valuable for optimizing drug candidates targeting autoimmune conditions such as rheumatoid arthritis and psoriasis. Commonly employed in preclinical studies to evaluate efficacy, pharmacokinetics, and target modulation in cellular and animal models.