trans-3-(Cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile
98%
science Other reagents with same CAS 2127109-84-4
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Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 2 (JAK2), particularly in the development of treatments for myeloproliferative disorders. Shows promising activity in suppressing abnormal cell signaling associated with JAK2 mutations, such as V617F. Investigated for its potential in treating conditions like polycythemia vera and myelofibrosis due to its ability to modulate inflammatory and proliferative pathways. Also employed as a chemical probe to study JAK-STAT signaling in cellular models.
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