trans-3-(Cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile

98%

Reagent Code: #165866
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CAS Number 2127109-84-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 383.41 g/mol
Formula C₂₀H₁₇N₉
badge Registry Numbers
MDL Number MFCD32197240
inventory_2 Storage & Handling
Density 1.46±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 2 (JAK2), particularly in the development of treatments for myeloproliferative disorders. Shows promising activity in suppressing abnormal cell signaling associated with JAK2 mutations, such as V617F. Investigated for its potential in treating conditions like polycythemia vera and myelofibrosis due to its ability to modulate inflammatory and proliferative pathways. Also employed as a chemical probe to study JAK-STAT signaling in cellular models.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿11,520.00
inventory 10mg
10-20 days ฿21,680.00
inventory 25mg
10-20 days ฿45,350.00
inventory 50mg
10-20 days ฿70,730.00

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