4-(((4-(5-Chloro-2-((trans-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile
98%
Reagent
Code: #164928
CAS Number
2247481-21-4
blur_circular Chemical Specifications
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Storage & Handling
Storage
-20°C, drying away from light
description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9. It plays a key role in studies targeting transcription regulation in cancer cells, showing promise in the development of anticancer therapies. The compound is investigated for its ability to induce apoptosis in tumor cells by blocking the phosphorylation of RNA polymerase II, thereby disrupting oncogenic transcription. It is also utilized in biochemical assays to study cell cycle progression and transcriptional control mechanisms.
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