CHMFL-FLT3-122
98%
Reagent
Code: #164635
CAS Number
1839150-56-9
blur_circular Chemical Specifications
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Molecular Information
Weight
471.57 g/mol
Formula
C₂₆H₂₉N₇O₂
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Storage & Handling
Storage
-20°C
description Product Description
Used as a potent and selective inhibitor of FLT3 kinase in research settings, particularly in studies related to acute myeloid leukemia (AML). It helps in blocking aberrant signaling pathways driven by FLT3 mutations, such as internal tandem duplications (ITD) and tyrosine kinase domain (TKD) mutations. Commonly applied in cellular and biochemical assays to evaluate anti-leukemic activity, assess pathway inhibition, and support the development of targeted cancer therapies. Its selectivity makes it a valuable tool for probing FLT3-dependent cell proliferation and survival mechanisms.
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