Used primarily in research settings as a potent inhibitor of vascular endothelial growth factor receptor (VEGFR) tyrosine kinases. It demonstrates significant antiangiogenic activity, making it valuable in studies related to cancer therapy, particularly in inhibiting tumor growth and metastasis by blocking the formation of new blood vessels that supply tumors. Its structure allows for strong binding to kinase domains, enhancing its effectiveness in cellular assays. Commonly employed in preclinical studies to evaluate signaling pathways involved in tumor progression and angiogenesis.