Used primarily in cancer treatment, particularly in clinical research for solid tumors such as lung, ovarian, and brain cancers. It works by inhibiting vascular endothelial growth factor receptors (VEGFRs), which play a key role in tumor angiogenesis—the formation of new blood vessels that supply tumors with nutrients and oxygen. By blocking these receptors, the compound helps suppress tumor growth and spread. It has been investigated in combination with chemotherapy and other targeted therapies to enhance anti-tumor effects. Research also explores its potential in overcoming resistance to other anti-angiogenic drugs.