leniolisib(CDZ 173)
10mM in DMSO
Reagent
Code: #158033
CAS Number
1354690-24-6
blur_circular Chemical Specifications
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Molecular Information
Weight
450.46 g/mol
Formula
C₂₁H₂₅F₃N₆O₂
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Storage & Handling
Storage
-20°C
description Product Description
Used to treat activated phosphoinositide 3-kinase delta syndrome (APDS), a rare primary immunodeficiency disorder. It works by selectively inhibiting the PI3K delta enzyme, which plays a key role in the overactivation of immune cells seen in APDS. By modulating this pathway, it helps reduce lymphoproliferation, improves immune function, and decreases the frequency of infections in affected patients. It is taken orally and is designed for long-term management of the condition, particularly in adults and children over 12 years old.
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