Used primarily in research settings, this compound functions as a potent inhibitor of JAK1 and JAK2 kinases, making it valuable in studying signaling pathways involved in inflammation, autoimmune disorders, and hematological cancers. It has shown efficacy in preclinical models of myeloproliferative neoplasms, particularly those driven by JAK2 mutations such as JAK2V617F. Researchers utilize it to investigate mechanisms of cytokine signaling and to evaluate therapeutic strategies for diseases like myelofibrosis and polycythemia vera. Its ability to cross the blood-brain barrier also allows exploration of neuroinflammatory conditions and central nervous system involvement in JAK-STAT-related pathologies.