CO-1686 (AVL-301)

10mM in DMSO

Reagent Code: #157801
fingerprint
CAS Number 1374640-70-6

science Other reagents with same CAS 1374640-70-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 555.55 g/mol
Formula C₂₇H₂₈F₃N₇O₃
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in targeted cancer therapy, particularly for non-small cell lung cancer with specific EGFR mutations. It selectively inhibits mutant forms of EGFR, including the T790M resistance mutation, while sparing wild-type EGFR, reducing side effects. This makes it effective in patients who have developed resistance to first-generation EGFR inhibitors. Its design allows for sustained target inhibition and improved therapeutic outcomes in refractory cases.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿6,100.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB
CO-1686 (AVL-301)
No image available
Used in targeted cancer therapy, particularly for non-small cell lung cancer with specific EGFR mutations. It selectively inhibits mutant forms of EGFR, including the T790M resistance mutation, while sparing wild-type EGFR, reducing side effects. This makes it effective in patients who have developed resistance to first-generation EGFR inhibitors. Its design allows for sustained target inhibition and improved therapeutic outcomes in refractory cases.
Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Purchase History for

Loading purchase history...