Used primarily in research as a potent inhibitor of vascular endothelial growth factor receptor (VEGFR) signaling pathways. It demonstrates significant antitumor activity by suppressing angiogenesis, the process by which tumors develop new blood vessels to support their growth. This compound is especially valuable in studies focused on cancer therapeutics, including models of renal cell carcinoma and other solid tumors. Its structure allows for strong binding to tyrosine kinase domains, making it a key scaffold in the development of targeted cancer therapies. Also employed in biochemical assays to probe signaling mechanisms in endothelial and cancer cells.