Used in research for its potent irreversible inhibition of the epidermal growth factor receptor (EGFR), making it a valuable tool in studies targeting cancer cell proliferation and survival, particularly in non-small cell lung cancer and other solid tumors. It helps scientists understand resistance mechanisms to EGFR inhibitors and supports the development of next-generation targeted therapies. Due to its irreversible binding, it provides sustained suppression of EGFR signaling in experimental models, enhancing the evaluation of downstream pathway effects.