N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate

10mM in DMSO

Reagent Code: #157443
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Alias Cabotinib malate; Cabotinib malate; XL184 S-malate; BMS-907351 S-malate
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CAS Number 1140909-48-3

science Other reagents with same CAS 1140909-48-3

blur_circular Chemical Specifications

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Weight 635.60 g/mol
Formula C₂₈H₂₄FN₃O₅.C₄H₆O₅
inventory_2 Storage & Handling
Storage -20℃

description Product Description

Used in pharmaceutical research as a potent inhibitor of receptor tyrosine kinases, particularly targeting pathways involved in cancer cell proliferation and angiogenesis. Demonstrates strong activity in suppressing tumor growth in preclinical models, especially in solid tumors such as lung, breast, and colon cancers. Its structure enables high selectivity and improved pharmacokinetic properties, making it a candidate for targeted cancer therapy development. Also investigated for overcoming resistance to existing kinase inhibitors due to its unique binding mechanism. Currently utilized in experimental studies to evaluate efficacy, safety, and optimal dosing regimens in oncology.

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inventory 1ml
10-20 days ฿7,840.00

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N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate
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Used in pharmaceutical research as a potent inhibitor of receptor tyrosine kinases, particularly targeting pathways involved in cancer cell proliferation and angiogenesis. Demonstrates strong activity in suppressing tumor growth in preclinical models, especially in solid tumors such as lung, breast, and colon cancers. Its structure enables high selectivity and improved pharmacokinetic properties, making it a candidate for targeted cancer therapy development. Also investigated for overcoming resistance to existing kinase inhibitors due to its unique binding mechanism. Currently utilized in experimental studies to evaluate efficacy, safety, and optimal dosing regimens in oncology.
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