2-Cyclobutyl-10-methyl-3-phenylpyrimido[4,5-b]quinoline-4,5(3H,10H)-dione
97%
Reagent
Code: #157165
CAS Number
1613509-49-1
blur_circular Chemical Specifications
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Molecular Information
Weight
357.4052 g/mol
Formula
C₂₂H₁₉N₃O₂
thermostat
Physical Properties
Boiling Point
495.3±55.0 °C(Predicted)
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Storage & Handling
Density
1.35±0.1 g/cm3(Predicted)
Storage
-20°C
description Product Description
Used in research as a potent inhibitor of cyclin-dependent kinases (CDKs), particularly CDK2 and CDK4, making it valuable in studies related to cell cycle regulation and cancer development. Shows promise in preclinical models for antitumor activity due to its ability to induce cell cycle arrest and apoptosis in cancer cells. Also employed as a molecular probe to investigate signaling pathways involved in proliferation and transcription. Its selective kinase inhibition profile supports its use in developing targeted cancer therapies.
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