4-((3-Chloro-4-fluorophenyl)amino)-6-methoxyquinazolin-7-ol
95%
Reagent
Code: #156880
CAS Number
451494-91-0
science Other reagents with same CAS 451494-91-0
blur_circular Chemical Specifications
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Molecular Information
Weight
319.72 g/mol
Formula
C₁₅H₁₁ClFN₃O₂
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Storage & Handling
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a critical role in the development of pharmaceuticals that inhibit abnormal protein signaling in tumor cells, especially in non-small cell lung cancer and other solid tumors. Its structure allows selective binding to epidermal growth factor receptor (EGFR), making it valuable in creating drugs that block cancer cell proliferation and promote apoptosis. Commonly utilized in research and industrial settings for developing potent, orally active anticancer agents.
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