7-(But-2-yn-1-yl)-8-((2-hydroxyethyl)amino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

97%

Reagent Code: #154800
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CAS Number 2074688-84-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 433.46 g/mol
Formula C₂₂H₂₃N₇O₃
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9, in biochemical and cellular research. It is employed to study transcriptional regulation, as CDK9 plays a key role in RNA polymerase II-mediated gene expression. The compound shows utility in cancer research due to its ability to induce apoptosis in tumor cells by disrupting the phosphorylation of key transcriptional regulators. It is also used in combination studies with other anticancer agents to evaluate synergistic effects and overcome drug resistance. Its cell permeability and stability make it suitable for in vitro and in vivo assays targeting kinase-dependent pathways.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿250,000.00

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