Used as a potent inhibitor of cyclin-dependent kinases (CDKs), particularly CDK2 and CDK9, this compound plays a significant role in cancer research. It interferes with cell cycle progression and transcription in tumor cells, leading to apoptosis. It is widely employed in preclinical studies to evaluate the effects of CDK inhibition on various cancer types, including leukemia and solid tumors. Its ability to cross the blood-brain barrier also makes it useful in studying central nervous system malignancies. Additionally, it serves as a valuable tool compound for understanding the biological roles of specific CDKs in cellular processes.