5-Bromo-3-ethylindolin-2-one
97%
Reagent
Code: #153265
CAS Number
304876-05-9
blur_circular Chemical Specifications
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Molecular Information
Weight
240.1 g/mol
Formula
C₁₀H₁₀BrNO
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Storage & Handling
Storage
2-8°C, drying away from light
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in medicinal chemistry due to its indolinone scaffold, which is known for biological activity in cell signaling pathways. Commonly employed in the preparation of tyrosine kinase and cyclin-dependent kinase inhibitors. Also utilized in research settings for structure-activity relationship (SAR) studies to optimize drug candidates. Its bromo functionality allows for further derivatization via cross-coupling reactions such as Suzuki or Heck reactions, enabling rapid generation of compound libraries for drug discovery.
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