6-Benzyl-3-(3-(thiazol-5-ylmethoxy)phenyl)-3,4-dihydropyrido[4,3-d]pyrimidine-2,7(1H,6H)-dione
98%
Reagent
Code: #151654
CAS Number
2104030-82-0
blur_circular Chemical Specifications
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Molecular Information
Weight
444.514 g/mol
Formula
C₂₄H₂₀N₄O₃S
thermostat
Physical Properties
Boiling Point
777.4±60.0 °C(Predicted)
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Storage & Handling
Density
1.44±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9, which plays a key role in transcription regulation. This compound shows promise in oncology for targeting cancer cells by disrupting the transcriptional machinery necessary for tumor growth and survival. It is investigated for its antiproliferative effects in hematological malignancies and solid tumors. Additionally, due to its ability to modulate RNA polymerase II activity via CDK9 inhibition, it serves as a tool compound in studying transcriptional control in cellular models.
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