6-Benzyl-3-(3-(thiazol-5-ylmethoxy)phenyl)-3,4-dihydropyrido[4,3-d]pyrimidine-2,7(1H,6H)-dione
98%
science Other reagents with same CAS 2104030-82-0
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Used in pharmaceutical research as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9, which plays a key role in transcription regulation. This compound shows promise in oncology for targeting cancer cells by disrupting the transcriptional machinery necessary for tumor growth and survival. It is investigated for its antiproliferative effects in hematological malignancies and solid tumors. Additionally, due to its ability to modulate RNA polymerase II activity via CDK9 inhibition, it serves as a tool compound in studying transcriptional control in cellular models.
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