2-(3-Bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one
95%
Reagent
Code: #151287
CAS Number
438450-43-2
blur_circular Chemical Specifications
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Molecular Information
Weight
465.13 g/mol
Formula
C₁₈H₁₂BrCl₂N₅O
thermostat
Physical Properties
Melting Point
210 - 215 °C
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Storage & Handling
Storage
-20℃, Inert gas
description Product Description
Used as a key intermediate in the synthesis of potent kinase inhibitors, particularly in the development of targeted cancer therapies. It exhibits strong activity against tyrosine kinases involved in tumor growth and angiogenesis. Due to its halogenated structure, it allows for further functionalization via cross-coupling reactions, making it valuable in medicinal chemistry for optimizing drug candidates. It is primarily employed in research settings for designing inhibitors with improved selectivity and pharmacokinetic profiles.
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