(1-(tert-Butoxycarbonyl)-5-cyano-1H-indol-2-yl)boronic acid

95%

Reagent Code: #150612
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CAS Number 475102-15-9

science Other reagents with same CAS 475102-15-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 286.09 g/mol
Formula C₁₄H₁₅BN₂O₄
badge Registry Numbers
MDL Number MFCD04114578
inventory_2 Storage & Handling
Storage -20°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure, featuring a tert-butoxycarbonyl protecting group, cyano substituent, and boronic acid moiety, enables selective cross-coupling reactions, making it valuable in constructing complex indole-based molecules. Commonly employed in Suzuki-Miyaura coupling reactions to form biaryl systems found in bioactive molecules. Also utilized in medicinal chemistry for lead optimization due to its ability to enhance binding affinity and metabolic stability in drug candidates.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿790.00
inventory 250mg
10-20 days ฿1,500.00
inventory 1g
10-20 days ฿3,950.00
inventory 5g
10-20 days ฿19,510.00

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(1-(tert-Butoxycarbonyl)-5-cyano-1H-indol-2-yl)boronic acid
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Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure, featuring a tert-butoxycarbonyl protecting group, cyano substituent, and boronic acid moiety, enables selective cross-coupling reactions, making it valuable in constructing complex indole-based molecules. Commonly employed in Suzuki-Miyaura coupling reactions to form biaryl systems found in bioactive molecules. Also utilized in medicinal chemis

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure, featuring a tert-butoxycarbonyl protecting group, cyano substituent, and boronic acid moiety, enables selective cross-coupling reactions, making it valuable in constructing complex indole-based molecules. Commonly employed in Suzuki-Miyaura coupling reactions to form biaryl systems found in bioactive molecules. Also utilized in medicinal chemistry for lead optimization due to its ability to enhance binding affinity and metabolic stability in drug candidates.

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