(5'-BroMo-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-ylMethyl)-carbaMic acid tert-butyl ester

≥95%

Reagent Code: #149730
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CAS Number 1289007-64-2

science Other reagents with same CAS 1289007-64-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 370.28 g/mol
Formula C₁₆H₂₄BrN₃O₂
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

Used as a protected intermediate in the synthesis of pharmaceutical compounds. The 5'-bromo substituent on the pyridine ring enables palladium-catalyzed cross-coupling reactions for further derivatization, while the tert-butyl carbamate (Boc) protecting group on the 4-(aminomethyl)piperidine allows for controlled deprotection and selective modification. This structure is valuable in medicinal chemistry for optimizing drug candidates, including kinase inhibitors for cancer treatment and potential CNS therapeutics, enhancing potency, selectivity, metabolic stability, and binding affinity. Commonly employed in research, solid-phase synthesis, and combinatorial chemistry.

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inventory 1g
10-20 days ฿41,290.00

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(5'-BroMo-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-ylMethyl)-carbaMic acid tert-butyl ester
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Used as a protected intermediate in the synthesis of pharmaceutical compounds. The 5'-bromo substituent on the pyridine ring enables palladium-catalyzed cross-coupling reactions for further derivatization, while the tert-butyl carbamate (Boc) protecting group on the 4-(aminomethyl)piperidine allows for controlled deprotection and selective modification. This structure is valuable in medicinal chemistry for optimizing drug candidates, including kinase inhibitors for cancer treatment and potential CNS ther

Used as a protected intermediate in the synthesis of pharmaceutical compounds. The 5'-bromo substituent on the pyridine ring enables palladium-catalyzed cross-coupling reactions for further derivatization, while the tert-butyl carbamate (Boc) protecting group on the 4-(aminomethyl)piperidine allows for controlled deprotection and selective modification. This structure is valuable in medicinal chemistry for optimizing drug candidates, including kinase inhibitors for cancer treatment and potential CNS therapeutics, enhancing potency, selectivity, metabolic stability, and binding affinity. Commonly employed in research, solid-phase synthesis, and combinatorial chemistry.

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