(5'-BroMo-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-ylMethyl)-carbaMic acid tert-butyl ester
≥95%
science Other reagents with same CAS 1289007-64-2
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description Product Description
Used as a protected intermediate in the synthesis of pharmaceutical compounds. The 5'-bromo substituent on the pyridine ring enables palladium-catalyzed cross-coupling reactions for further derivatization, while the tert-butyl carbamate (Boc) protecting group on the 4-(aminomethyl)piperidine allows for controlled deprotection and selective modification. This structure is valuable in medicinal chemistry for optimizing drug candidates, including kinase inhibitors for cancer treatment and potential CNS therapeutics, enhancing potency, selectivity, metabolic stability, and binding affinity. Commonly employed in research, solid-phase synthesis, and combinatorial chemistry.
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