tert-Butyl (2-chloropyrimidin-4-yl)carbamate

95%

Reagent Code: #148661
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CAS Number 849751-48-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 229.66 g/mol
Formula C₉H₁₂ClN₃O₂
badge Registry Numbers
MDL Number MFCD16036511
inventory_2 Storage & Handling
Storage 2-8°C, stored in inert gas

description Product Description

Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in medicinal chemistry due to the reactivity of the chloropyrimidine ring, allowing for selective substitutions that lead to biologically active molecules. Commonly employed in the preparation of targeted therapies, including inhibitors of EGFR, ALK, and other tyrosine kinases. Its tert-butoxycarbonyl (Boc) protecting group stabilizes the amine during synthesis and can be easily removed under mild acidic conditions, enabling further functionalization in multi-step reactions. Also utilized in agrochemical research for designing novel active ingredients with improved selectivity and stability.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿1,560.00
inventory 1g
10-20 days ฿3,900.00
inventory 5g
10-20 days ฿16,910.00

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