Used in research for the treatment of myelofibrosis, a type of bone marrow cancer. It functions as a selective inhibitor of JAK2 kinase, which plays a key role in signaling pathways involved in blood cell production. By targeting JAK2, it helps reduce abnormal cell growth and inflammation in the bone marrow. It has shown potential in alleviating symptoms such as spleen enlargement and systemic symptoms like fatigue and weight loss in preclinical models. Currently, it remains an investigational compound primarily used in laboratory and animal studies to understand JAK-STAT pathway modulation.