Bohemine is primarily used in scientific research as a selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK1, CDK2, and CDK5. Its main application lies in cell cycle studies, where it helps researchers understand the regulation of cell division and the role of CDKs in cellular processes. Due to its ability to arrest cells at specific phases of the cell cycle, Bohemine is employed in experiments involving cell synchronization and apoptosis. It has also been investigated for its potential in neuroprotection, as inhibition of CDK5 has been linked to reduced neuronal death in models of neurodegenerative diseases. Additionally, Bohemine serves as a tool compound in cancer research, helping to evaluate the effects of CDK inhibition on tumor cell proliferation and survival.