Used in research for treating cancers with FGFR (fibroblast growth factor receptor) pathway mutations, particularly in bladder, lung, and liver cancers. Shows activity against tumors with FGFR1, FGFR2, and FGFR3 alterations. Investigated in clinical trials for advanced solid tumors, especially cholangiocarcinoma and urothelial carcinoma. Also used as a tool compound to study FGFR signaling in cellular and animal models.