BMS-754807
10mM in DMSO
Reagent
Code: #142462
CAS Number
1001350-96-4
blur_circular Chemical Specifications
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Molecular Information
Weight
461.49 g/mol
Formula
C₂₃H₂₄FN₉O
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Registry Numbers
MDL Number
MFCD18633202
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in cancer research, particularly for studying insulin-like growth factor receptor (IGF-1R) signaling pathways. Shows potent inhibitory activity against IGF-1R and insulin receptor (IR), making it a valuable tool in exploring tumor growth inhibition in various cancers, including breast, lung, and colorectal. Also investigated for its effects on reversing resistance to other targeted therapies. Commonly used in preclinical studies to evaluate antiproliferative and pro-apoptotic effects in cell lines and animal models.
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