(3-Amino-2,6-Difluorophenyl)(5-(2-Cyclopropylpyrimidin-5-Yl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Methanone
97%
science Other reagents with same CAS 1859158-65-8
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description Product Description
Used as a key intermediate in the synthesis of Janus kinase (JAK) inhibitors, particularly in the development of pharmaceuticals targeting inflammatory and autoimmune diseases such as rheumatoid arthritis and psoriasis. Its structure enables selective inhibition of JAK1 and JAK2 enzymes, contributing to modulation of cytokine signaling pathways. This compound is also employed in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new drug candidates in clinical and preclinical research.
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