ASP5878
10mM in DMSO
Reagent
Code: #134168
CAS Number
1453208-66-6
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
407.37 g/mol
Formula
C₁₈H₁₉F₂N₅O₄
inventory_2
Storage & Handling
Storage
-20°C
description Product Description
Used in research as a selective inhibitor of AXL kinase, a receptor tyrosine kinase implicated in cancer progression and metastasis. Shows potential in oncology studies, particularly in models of acute myeloid leukemia and solid tumors, where AXL signaling contributes to drug resistance and immune evasion. Investigated for its ability to enhance the efficacy of other anticancer agents, including chemotherapy and immune checkpoint inhibitors, by modulating tumor microenvironment and suppressing survival pathways in malignant cells. Currently in preclinical development, serving as a tool compound to explore AXL-dependent signaling mechanisms and therapeutic strategies.
shopping_cart Available Sizes & Pricing
Cart
No products
Subtotal:
0.00
Total
0.00
THB