ASP5878

10mM in DMSO

Reagent Code: #134168
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CAS Number 1453208-66-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 407.37 g/mol
Formula C₁₈H₁₉F₂N₅O₄
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in research as a selective inhibitor of AXL kinase, a receptor tyrosine kinase implicated in cancer progression and metastasis. Shows potential in oncology studies, particularly in models of acute myeloid leukemia and solid tumors, where AXL signaling contributes to drug resistance and immune evasion. Investigated for its ability to enhance the efficacy of other anticancer agents, including chemotherapy and immune checkpoint inhibitors, by modulating tumor microenvironment and suppressing survival pathways in malignant cells. Currently in preclinical development, serving as a tool compound to explore AXL-dependent signaling mechanisms and therapeutic strategies.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿6,480.00

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