1-(2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea
95%
Reagent
Code: #133072
CAS Number
1135256-66-4
blur_circular Chemical Specifications
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Molecular Information
Weight
405.28 g/mol
Formula
C₁₈H₁₈Cl₂N₆O
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Storage & Handling
Density
1.416±0.06 g/cm3(Predicted)
Storage
2-8°C, light-proof, inert gas
description Product Description
Used in pharmaceutical research as a potent inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9, which plays a key role in transcription regulation. This compound shows promise in oncology for targeting cancer cells by disrupting the transcriptional machinery necessary for tumor growth and survival. It is investigated for its antiproliferative effects in hematological malignancies and solid tumors. Its selective kinase inhibition profile makes it a valuable tool compound in studying signaling pathways involved in cell cycle progression and apoptosis.
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