SBI-0206965 is primarily utilized in research settings as a potent and selective inhibitor of ULK1, a kinase involved in autophagy regulation. Its application is significant in studying autophagy pathways, particularly in understanding how inhibiting ULK1 affects cellular processes like nutrient sensing, stress responses, and cancer cell survival. Researchers use it to explore potential therapeutic strategies for diseases where autophagy plays a critical role, such as cancer, neurodegenerative disorders, and metabolic conditions. Additionally, it aids in elucidating the molecular mechanisms of autophagy and its interplay with other cellular signaling pathways.